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Efficacy and Safety Prediction of Milrinone or Levosimendan as Initial Inotropic Drug Therapy in Patients With Acute and Advanced Heart Failure With Renal Insufficiency

Exploring Milrinone or Levosimendan for heart and kidney health in trials.

Recruiting
18-80 years
All
Phase N/A
**Heart Failure Drug Study Summary** This study is testing two medicines, *milrinone* and *levosimendan*, for people with heart failure. Heart failure is when the heart can't pump blood well. The study focuses on those with kidney problems too, which affects how the body handles these drugs. *Inotropic drugs* like milrinone and levosimendan help the heart pump better. **Key Points:** - Study is for adults aged 18-80 with heart failure and certain heart function measures. - Participants should not have certain other heart conditions, recent surgeries, or severe kidney/liver issues. - This study helps doctors predict which drug is safer and more effective for different patients. Participants will be evaluated to see how well these medicines work and how safe they are. Only those without severe conditions and who haven't used similar medications recently can join. This research can guide future treatments for heart failure patients with kidney issues.
Study details
    Heart Failure
    Levosimendan
    Milrinone
    Efficacy
    Safety

NCT06205758

Yi Han

24 January 2024

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