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A Study to Customize Ibrutinib Treatment Regimens for Participants With Previously Untreated Chronic Lymphocytic Leukemia

Join a study about personalized ibrutinib treatment for untreated CLL patients.

Recruiting
18 years and older
All
Phase 2
**Study Summary:** This study looks at different ways to use a medicine called *ibrutinib* for people with a type of blood cancer called **Chronic Lymphocytic Leukemia (CLL)**. *Ibrutinib* is sometimes mixed with another medicine, *venetoclax*. The study is trying to see if changing the dose of *ibrutinib* can help reduce side effects. **Chronic Lymphocytic Leukemia (CLL)** is a type of cancer that affects white blood cells. To join the study, you must have CLL or a similar condition called **Small Lymphocytic Lymphoma (SLL)**. You also need to be able to take care of yourself pretty well according to a scale called **ECOG Performance Status**. Women in the study must use birth control and agree not to get pregnant. Some conditions, like certain heart diseases or other blood problems, mean you can't join. **Key Points:** - **Length of Study:** Details on the duration are not provided, but participants must agree to follow all study rules. - **Visits Needed:** Participants will need to attend regular visits for check-ups and to get medicine. - **Compensation:** There may be compensation, although it is not specifically mentioned in the study details.

It's important to talk to your doctor to see if you qualify and if this study is right for you.

Study details
    Leukemia
    Lymphocytic
    Chronic
    B-Cell
    Small Lymphocytic Lymphoma

NCT05963074

Janssen Research & Development, LLC

14 July 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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