Image

A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

Comparing new treatment to standard for multiple myeloma patients.

Recruiting
18 years and older
All
Phase 3

Study Overview: This study is testing a new treatment called arlo-cel (BMS-986393) to see if it's better and safer than usual treatments for adults who have a type of blood cancer called Multiple Myeloma. Multiple Myeloma is a cancer of the plasma cells, a type of white blood cell found in bone marrow. The study is for people whose cancer has returned or didn't respond to initial treatments and have already taken a drug called Lenalidomide.

Eligibility: To join, participants must have a confirmed diagnosis of Relapsed or Refractory Multiple Myeloma (RRMM), which means the cancer has either come back or isn’t responding to treatment. They've tried 1 to 3 different treatments before, and should have good organ function and an active disease that can be measured. They can't have involvement of the central nervous system by the cancer or need immediate treatment due to fast cancer growth.

  • The study compares a new treatment to standard ones.
  • Participants need to have tried specific cancer treatments before.
  • People with fast-growing or brain-involved cancer cannot join.
Study details
    Relapsed or Refractory Multiple Myeloma (RRMM)

NCT06615479

Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

24 June 2026

Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team


Email

View email

Phone

Phone country flag

View phone
Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.