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A Study to Evaluate Efficacy and Safety of Ciltacabtagene Autoleucel

Testing Ciltacabtagene Autoleucel for effectiveness and safety.

Recruiting
18-80 years
All
Phase 2
This study is testing how well a new treatment, called **cilta-cel**, works with different types of medicine plans for people with a disease called multiple myeloma. Multiple myeloma is a type of cancer that affects white blood cells. The study involves a process called **lymphodepletion**, which reduces the number of certain blood cells and is usually done with chemotherapy. **Key Points:** - Participants must have a new diagnosis of multiple myeloma and have received 3 to 5 cycles of induction therapy. - This study involves taking medicines that may include cyclophosphamide and fludarabine, which are types of chemotherapy drugs. - Participants should be able to follow specific lifestyle rules during the study and should not have severe ongoing side effects from previous treatments. If you decide to join, you will be part of a research study to help find better treatments for multiple myeloma. Make sure to discuss with your doctor whether this study is a good fit for you, considering your health condition and treatment history.
Study details
    Multiple Myeloma

NCT07149857

Janssen Research & Development, LLC

8 June 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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