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Dosimetry and Preliminary Clinical Application Study of a Novel Probe Targeting CD73

Studying a new probe for CD73 in a clinical setting.

Recruiting
18-90 years
All
Phase 0
  • Simplified description (AI rewritten)
  • Technical description (Original)

Study Overview: This study focuses on a new imaging agent called 68Ga-dPNE, which targets a protein known as CD73. CD73 helps cancer cells hide from the body's immune system. The study compares the effectiveness and safety of 68Ga-dPNE with another imaging agent, 18F-FDG.

Key Terms:

  • CD73: An enzyme linked to cancer growth.
  • PET Radiotracer: A substance used in scans to help see cancer in the body.
  • Biodistribution: How a substance spreads in the body.
  • Dosimetry: The study of radiation doses in the body.

Eligibility: To participate, you must sign consent and follow up. You cannot participate if you are pregnant, breastfeeding, or have severe liver or kidney problems.

  • Study involves imaging and comparing two agents.
  • Participants need to give informed consent.
  • Study assesses safety and spread of 68Ga-dPNE in the body.
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Study details
    Malignant Tumour

NCT06995976

First Affiliated Hospital of Fujian Medical University

8 August 2025

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