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A Study to Evaluate the Safety, PK/PD of (OriCAR-017) in Subjects With RR/MM - RIGEL Study

Join a study evaluating OriCAR-017's effects on certain blood cancers.

Recruiting
18-75 years
All
Phase 1

This study aims to test a new treatment for people with relapsed or refractory multiple myeloma (RR/MM). Multiple myeloma is a type of blood cancer. The treatment being studied is called OriCAR-017, which is a special kind of cell product designed to target a protein called GPRC5D. This is a Phase I/II study, meaning it's in the early stages of testing. It will check how safe the treatment is, how it moves and acts in the body (pharmacokinetics and pharmacodynamics), and if it seems to be working.

The study involves different stages. The first stage will test three different doses in 18 people. The next stages will include more people to further check the treatment's effects. Participants need to be 18 to 75 years old and meet specific health criteria. The study will not accept pregnant women, people with certain infections, or those who have had recent stem cell treatments.

  • The study involves multiple stages and will require several visits.
  • Participants need to have had certain previous treatments.
  • Effective contraceptive measures are required for two years after treatment.
Study details
    Multiple Myeloma

NCT06271252

OriCell Therapeutics Co., Ltd.

11 July 2024

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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