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A Study to Evaluate the Safety, Effectiveness and Tolerable Dose of BMS-986393 in Novel Combinations in Participants With Relapsed and/or Refractory Multiple Myeloma

Testing a new treatment for multiple myeloma safety and effectiveness.

Recruiting
18 years and older
All
Phase 1
**Study Overview:** This research is for people with *relapsed* or *refractory multiple myeloma* (RRMM). Multiple myeloma is a type of blood cancer that affects plasma cells in the bone marrow. *Relapsed* means the cancer has returned after treatment, and *refractory* means the cancer didn’t respond to treatment. The study aims to find a safe dose of a new drug, BMS-986393, combined with other medicines (alnuctamab, mezigdomide, and iberdomide) for treating RRMM. **Key Points:** - **Duration & Visits:** Participation may require multiple visits to the study site over a period of time, although exact details are not specified. - **Eligibility:** You must have been treated with at least one prior anti-myeloma treatment and have measurable multiple myeloma. - **Risks & Benefits:** While this study may offer potential benefits, such as disease management, it may also involve risks like side effects from the new drug combinations. Before considering participation, discuss with your doctor to understand the potential effects on your health. Always consider both the benefits and risks when deciding on joining a clinical trial.
Study details
    Multiple Myeloma

NCT06121843

Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

11 July 2024

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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