**Study Summary** This study looks at how well a new asthma treatment, called FF/UMEC/VI, works compared to regular treatments (ICS/LABA) for adults with uncontrolled asthma. "Uncontrolled asthma" means asthma is not well-managed. FF/UMEC/VI combines three medicines: fluticasone furoate (FF), umeclidinium bromide (UMEC), and vilanterol trifenatate (VI). ICS and LABA are other medicines often used for asthma. To join this study, you need to have asthma, follow the Global Initiative for Asthma (GINA) rules, and have had it for at least 3 months. You should not have had severe asthma attacks recently or need certain types of asthma medicines. You also need to be able to answer study questions. **Key Points:** - **Length of Study:** Check the specific study duration before enrolling. - **Visits Needed:** Participants will need to complete various questionnaires. - **Eligibility:** There are specific inclusion and exclusion criteria, such as not being on certain medications recently and not having severe asthma history. This study helps researchers understand which treatment might work better for people with asthma. Always discuss with your doctor before joining any study.