Melasma is a skin problem that causes dark patches, affecting a person's looks and feelings. It's tough to treat, but we're testing if a medicine called oral isotretinoin can help. This study will check how well it works compared to the usual cream treatment. The study is for adults aged 18 to 50 with any type of melasma. Women participating need to use two types of birth control during the study. Pregnant or nursing women and those on melasma treatment recently can't join. People with liver problems or allergies to the study medicine will be excluded.

• This study may involve several visits to the clinic.
• Participants should avoid other melasma treatments during the study.
• There may be risks associated with isotretinoin, like back or joint pain.