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3D-MRE and 2D-MRE for Assessing Cirrhosis and Portal Hypertension

Testing liver health using advanced imaging techniques.

Recruiting
18-75 years
All
Phase N/A

This study compares two techniques, **3D-MRE** and **2D-MRE**, to improve the management of portal hypertension in people with cirrhosis. Cirrhosis is a liver condition often caused by long-term liver diseases like hepatitis or alcohol abuse. Portal hypertension refers to increased blood pressure in veins that supply the liver, which can be dangerous. The **hepatic venous pressure gradient (HVPG)** is a measure used to assess this hypertension, but it involves invasive procedures. The goal here is to find a non-invasive way to predict HVPG using magnetic resonance elastography (MRE), which is a type of MRI that measures the stiffness of tissues in the liver. This study will help determine if 3D-MRE is more effective than 2D-MRE.

  • This study requires participants to be over 18, have cirrhosis, and complete both 3D-MRE and 2D-MRE tests.
  • Involves attending medical appointments within one month before HVPG measurement.
  • Participants must not have had liver/spleen surgery, liver cancer, or unreliable test results.
Study details
    Cirrhosis
    Liver Portal Hypertension

NCT06205992

Shengjing Hospital

24 January 2024

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