**Study Summary** This study is focused on using a special technique called *NIR-II fluorescence imaging* during surgery to help doctors see liver cancer tumors more clearly. The imaging technique uses *ITGA6 targeting probes* to highlight the cancer cells. *Hepatocellular carcinoma* is a type of liver cancer. The aim is to see if this method can help surgeons remove the cancer more precisely and safely. **Eligibility Criteria**: To join, you must be between 18 and 80 years old, diagnosed with hepatocellular carcinoma, and scheduled for liver surgery. Your liver must be functioning well (Child-Pugh A), and you must not be allergic to *Cy7* (a dye used in the imaging process). You should not be part of another study within the last three months or have other serious health issues. **Key Points**: - The study involves undergoing surgery with special imaging. - It aims to improve tumor detection and surgical precision. - Participants should consider potential risks and benefits. The study evaluates if the new imaging method using ITGA6 is safe and effective for clinical use. If you meet the criteria and are interested, discussing with your doctor would be a good next step.