This clinical study is testing a treatment called **F01** to see if it's safe and okay to use for people with autoimmune diseases. Autoimmune diseases make the body's defense system attack itself, which can cause problems like pain or tiredness. The study includes people with conditions like systemic lupus erythematosus (SLE), vasculitis, inflammatory muscle diseases, and systemic sclerosis. **Key Points:** - The study has two parts: dose escalation (testing different amounts of F01) and dose extension (testing the best amount). - Up to **20 participants** will join, and each must be between **18 and 65 years old**. - Participants will go through different tests to ensure they are suitable and must agree to use effective birth control during and after the study. Before joining, make sure you understand the time commitment, any potential risks, and if the study fits your health needs. Participants will be closely monitored to ensure their safety throughout the study.