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The Antimicrobial Potential of Diclofenac Sodium as an Intracanal Medicament

Exploring diclofenac sodium as a potential tooth infection treatment.

Recruiting
18-50 years
All
Phase 2/3

This study is testing how well diclofenac sodium, a type of medicine, can kill bacteria in infected teeth. It will compare it to another common treatment called calcium hydroxide paste. Both of these are used as intracanal medications, which are placed inside the root canals of teeth to fight infection. The study will focus on patients with a condition called chronic apical periodontitis, an infection at the tip of a tooth root. The researchers will take samples from the teeth before and after treatment to see which medicine works better at reducing bacteria.

Key Points:

  • Participants will be divided into three equal groups randomly and treated with one of the medications.
  • This study only includes patients with adult molar teeth that have certain infections and are restorable.
  • People with certain medical conditions or allergies to diclofenac sodium cannot join the study.
Study details
    Endodontic Disease
    Pulp Disease
    Dental
    Intracanal Medication

NCT06207253

British University In Egypt

24 January 2024

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