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Microecology and Immunity in Patients With Anti-MDA5 Antibody Positive Dermatomyositis and Interstitial Lung Disease

Study on immunity and gut health in specific lung disease patients.

Recruiting
18 years and older
All
Phase N/A

This study is exploring how tiny living things, called microbes, and the body's defense system, or immunity, affect a disease called dermatomyositis with lung issues. Dermatomyositis is a condition that causes muscle weakness and skin rashes. Some people with this condition have special proteins called anti-MDA5 antibodies in their blood. The study focuses on patients who also have a serious lung disease called interstitial lung disease (ILD), which affects the tissue around the air sacs in the lungs. The researchers use a test called bronchoalveolar lavage to collect samples from the lungs to see how microbes and immunity relate to the disease.

  • Participants must be 18 or older and have a procedure called bronchoalveolar lavage.
  • The study involves people with specific conditions but excludes those with other tissue diseases or certain medical histories.
  • Participants must agree to join the study by signing a consent form.

Understanding this relationship could help develop better treatments for patients in the future.

Study details
    Microbiome
    Immune Function
    Anti-MDA5 Antibody Positive Dermatomyositis

NCT06203249

Chinese PLA General Hospital

24 January 2024

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