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Phase II Study of Concurrent Radiotherapy With Envafolimab and Capecitabine in LAPC

Exploring new treatment options for locally advanced pancreatic cancer.

Recruiting
18-90 years
All
Phase 2
This study is for people with advanced pancreatic cancer to see if combining radiation with two medicines, envafolimab and capecitabine, is effective and safe. **Radiotherapy** is a treatment using high-energy rays to kill cancer cells. **Envafolimab** is a medicine that helps the immune system fight cancer, and **capecitabine** is a chemotherapy pill taken to stop cancer cells from growing. **Key Points:** - The study uses a special type of radiotherapy and involves taking medicine by injection and pill. - Participants must not have cancer spread beyond specific areas and should not have certain health conditions. - Participation involves regular hospital visits and treatments, and may continue until the cancer worsens or the patient cannot tolerate the treatment. **Eligibility:** People aged 18-90 with non-removable pancreatic cancer that hasn't spread significantly. Participants must have good organ function and be willing to follow study procedures. Those with certain health conditions or treatments are not eligible.
Study details
    Pancreatic Cancer
    Radiotherapy
    Envafolimab
    Capecitabine

NCT06202014

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

24 January 2024

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