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FOLFOX-HAIC Plus Lenvatinib and Toripalimab vs. FOLFOX-HAIC Plus Lenvatinib for Advanced Hepatocellular Carcinoma: a Randomized Controlled and Double-blind Trial

Testing two treatments for advanced liver cancer in a research study.

Recruiting
18-75 years
All
Phase 3
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study aims to find the best treatment for advanced hepatocellular carcinoma, a type of liver cancer. Two treatments are compared: one with FOLFOX-HAIC plus lenvatinib and toripalimab, and another with FOLFOX-HAIC plus lenvatinib. FOLFOX-HAIC is a type of chemotherapy given directly to the liver through an artery. Lenvatinib is a drug that stops cancer from growing, while toripalimab is an antibody that helps the immune system fight cancer. The study is randomized (patients are randomly assigned a treatment) and double-blind (neither doctors nor patients know which treatment is given to prevent bias).

  • The study is for patients with advanced liver cancer who meet specific health criteria.
  • Participation requires understanding and signing a consent form.
  • Patients with certain health issues or those on specific medications may not qualify.
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Study details
    Hepatocellular Carcinoma

NCT06201065

Sun Yat-sen University

24 January 2024

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