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Organ Preservation First Strategy and Intentional Watch and Wait for MRI Defined Low-risk Rectal Cancer

Monitoring low-risk rectal cancer through MRI before considering treatment.

Recruiting
18-85 years
All
Phase N/A

This study is about testing new ways to treat low-risk rectal cancer using MRI images. Rectal cancer is a type of cancer that starts in the rectum, which is part of the large intestine. The study will look at two options after giving patients a special type of radiation therapy (called intensity modulated radiotherapy) and a combination of drugs (capecitabine and CapeOX). Patients may either have a small surgery (local excision) or be monitored closely without surgery (non-operative management). The goal is to see if these methods work well and are safe.

  • Length of Study: Participation involves treatment and monitoring, which may include surgery.
  • Eligibility: Must be 18 to 85 years old, with specific cancer characteristics, and no prior rectal cancer treatments.
  • Risks: Potential side effects from radiation, chemotherapy, or surgery, and the need for informed consent.
Study details
    Rectal Cancer

NCT06209099

Peking University Cancer Hospital & Institute

24 January 2024

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